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Deficiency of sympathetic activity in the unilateral face, also known as oculosympathetic palsy. What are some physical findings in Horner syndrome? Ptosis—eyelid drooping Anhidrosis—lack of sweating Miosis—constricted pupil Enophthalmos—inward deviation of eyeball Loss of ciliospinal reflex (pupil dilation in response to painful ipsilateral neck stimuli) *Typically all unilateral on affected side Name some commonly used medications for abortive therapy: Sumatriptan (selective 5-HT1B and 1D receptor agonist) High-flow oxygen Dihydroergotamine (vasoactive ergot derivative has many adverse reactions) Name some commonly used medications for prophylactic treatment: Beta-blockers Tricyclic antidepressants Calcium channel blockers Migraine List some defining features of migraine: Severe headache that afflicts millions Can be characterized by autonomic dysfunction It is more prevalent in women Often chronic and recurrent What are some signs and symptoms of a migraine?

Helps to distinguish between effective volume depletion and other causes What is the initial treatment in patients who are asymptomatic and have a plasma sodium concentration above 120 mEq/L? Gradual correction with water restriction or administration of isotonic saline. What are four things to consider when managing patients with hyponatremia? Estimate the sodium deficit if giving sodium What can lead to the development of central pontine myelinolysis? Rapid correction of severe hyponatremia What are some signs and symptoms of central pontine myelinolysis?

Whether the patient has a history of seizures The circumstances that led to the seizure Observed ictal behavior Identify potential triggers Loss of bladder/bowel function Current medication regimen Define partial seizures: Localized electrical discharge of the cerebral cortex; consciousness is often intact as it does not cross the midline of the brain. Define the following types of partial seizures: Simple partial No alteration of consciousness Symptoms based on cortex affected Visual changes if occipital area affected Complex partial Consciousness is impaired A simple partial with mentation affected Often due to discharge of temporal region Partial seizure with secondary generalization A seizure that starts localized and then spreads throughout the cerebrum Originally with localizing symptoms, then evolves into one of the types below Define generalized seizures Global discharge of both cerebral hemispheres that often results in loss of consciousness along with abnormal movements of the body.

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A Bayesian Approach to Weibull Survival Models - Application to a Cancer Clinical Trial by Abrams K.


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